Friday, April 1, 2011

Report: SLI support coming to AMD's 990-series chipsets

Remember when running a couple of GeForces in SLI mode required the use of an Nvidia nForce chipset? Things may have changed in the Intel camp, but AMD users are still faced with that old conundrum—and today, SLI-capable nForce 980a motherboards have all but disappeared from online listings.
A solution...

Source: http://techreport.com/discussions.x/20692

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Report: Sony PSP, NGP to get Music Unlimited

Sony's Music Unlimited service is on its way to the PlayStation Portable "in a matter of weeks" and also to the Next Generation Portable, a company exec tells Eurogamer.

Source: http://news.cnet.com/8301-13506_3-20049597-17.html?part=rss&subj=news&tag=2547-1_3-0-20

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Aviation Inspired Furniture

Inspired by World War II airplanes, Restoration Hardware created a series of unique furniture out of metal and aged leather.

Copenhagen Spitfire Chair
The creativity of Danish design found new expression in this cool chair.

Aviator Bookcase
Sleek looking bookcase wrapped in polished aluminum inside and out.

Aviator Chair
The design of this chair was inspired by fighter planes, from its [...]

Source: http://feedproxy.google.com/~r/toxel/~3/AzzPsYYdhW8/

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Appeals Court Still Says 'Down Under' Infringes On Decades Old Folk Song

A couple years ago, Australian music publisher Larrikin Music accused the iconic 80s Australian band "Men at Work" (and its label, EMI) of infringing on its copyright for the classic Australian folk song Kookaburra in their hit song Down Under. You can listen to both songs in the videos below:


If you can't tell (and some can't), a bit of the flute line in the Men at Work song is similar to the meldoy in Kookaburra. Most normal people would call this a tribute or an homage. But not Larrikin. The company, which only got the rights to Kookaburra (which was written in the '30s) in 2000, hadn't even noticed the similarity until it was mentioned in a game show on TV. So, of course, Larrikin sued. And, amazingly, it won... leading the court to grant Larrikin 5% of all of the song's earnings.

This is ridiculous for a variety of reasons. It's clearly not a straight copy, but a use of the well-known folk song to represent the atmosphere of Australia. The fact that Larrikin didn't even notice until it was pointed out on TV should also suggest that this wasn't some massive infringement issue. Finally, the fact that the song was a hit in the early '80s should have set off some sort of statute of limitations issue. Instead, Larrikin won...

EMI reasonably appealed the ruling, but chillienet points out that Larrikin has won on appeal as well, as a three-judge panel ruled that the song is infringing. The court even ordered EMI to pay the court costs as well. I guess the lesson is clear: don't promote decades old folk songs in your music in Australia.

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Source: http://www.techdirt.com/articles/20110331/03553613714/appeals-court-still-says-down-under-infringes-decades-old-folk-song.shtml

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PhotoSync is Best Way to Transfer iPad 2 Pictures to PC

Now that the iPad 2 has a camera, you will want to transfer photos to your computer taken on the tablet. PhotoSync ($1.99) is one of the best apps for�transferring�them to other iOS devices or to a computer. It does

Source: http://feedproxy.google.com/%7Er/notebooks/com/%7E3/tbzrmfbpsW0/

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Can Jack Dorsey Help Twitter Find Its Way?

Twitter co-founder Jack Dorsey is taking on an expanded role at the company, in what seems to be an attempt to show that Twitter is putting more emphasis back on the product after some recent mis-steps. Can Dorsey help put things back on the right track?

Source: http://feedproxy.google.com/~r/OmMalik/~3/-LNR8goV9sg/

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Mutations in tumor suppressor take other genes down with them

p53 is a potent tumor suppressor. Its job is to scan along DNA, identify mutations that might cause cancer, and then halt cell growth until they can be repaired—it kills the cell if they cannot. It is mutated in approximately 50 percent of human tumors, and in its absence, DNA mutations can accrue while the cell divides, often forming a tumor. But some p53 mutants exhibit a nefarious “dominant negative” effect: when they are around, they prevent wild-type (normal) p53 molecules from working. 

Because p53 works as a tetramer—a complex of four p53 molecules all bound together—it has generally been presumed that this dominant negative effect is achieved when mutant p53 molecules link up with normal counterparts to form nonfunctional tetramers. But new work reported in Nature Chemical Biology suggests that the process is more complex; some mutants can form much larger aggregates, not only with wild-type p53 but also with its related tumor suppressors p63 and p73. In addition to its blocking the function of these proteins, this aggregation can induce cellular changes that further contribute to tumorigenesis.

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Source: http://feeds.arstechnica.com/~r/arstechnica/index/~3/AlHM3CyMZFA/the-tumor-suppressor-p53-can-form-prion-like-aggregates-when-mutated.ars

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